Current Issue : January - March Volume : 2021 Issue Number : 1 Articles : 5 Articles
Background: Knee osteoarthritis (OA) is a common disabling disease involving the entire joint tissue, and its onset\nand progression are affected by many factors. However, the current number of studies investigating the relationship\nbetween subchondral trabecular bone (STB), knee alignment, and OA severity is limited. We aimed to investigate the\nvariation in tibial plateau STB microarchitecture in end-stage knee OA patients and their association with knee\nalignment (hip-knee-ankle, HKA, angle) and OA severity.\nMethods: Seventy-one knee OA patients scheduled for total knee arthroplasty (TKA) underwent preoperative\nradiography to measure the HKA angle and Kellgren-Lawrence grade. Tibial plateaus collected from TKA were\nscanned using micro-computed tomography to analyze the STB microarchitecture. Histological sections were\nused to assess cartilage degeneration (OARSI score). Correlations between the HKA angle, OA severity (OARSI\nscore, Kellgren-Lawrence grade), and STB microarchitecture were evaluated. Differences in STB microstructural\nparameters between varus and valgus alignment groups based on the HKA angle were examined........................
Objective: To evaluate intraobserver and interobserver reliability of the measurement\nof the mechanical axis of the lower limb by means of the panoramic\nradiograph of lower limbs by physicians with different levels of medical practice.\nMethod: A retrospective cross-sectional study with preoperative and\npostoperative radiographic analysis of a group of 100 patients submitted to total\nknee arthroplasty. Results: It was observed that there is a highly significant\nintraobserver and interobserver agreement...........................
Background: Individuals at risk of developing rheumatoid arthritis (RA) may benefit from lifestyle or pharmacological\ninterventions aimed at primary prevention. The same may apply to individuals at risk of axial spondyloarthritis (axSpA).\nOur aim was to investigate and compare the willingness of individuals at risk of RA or axSpA and rheumatologists to\ninitiate preventive intervention.\nMethods: Individuals at risk of RA (arthralgia and anti-citrullinated protein antibodies and/or rheumatoid factor\npositivity without arthritis (RA-risk cohort; n = 100)), axSpA (first-degree relatives of HLA-B27-positive axSpA patients\n(SpA-risk cohort; n = 38)), and Dutch rheumatologists (n = 49) completed a survey on preventive intervention which\nincluded questions about disease perception, lifestyle intervention, and preventive medication..................................
Introduction: With a considerable morbidity, mortality and a high financial\nimpact, PJI has been considered as one of the most serious complications after\narthroplasty. Special awareness must be given to these patients due to a\nlife threatening systemic PJI related complication, sepsis. A prompt detection\nand adequate medical management of this situation is crucial for avoiding\nunfavorable outcomes. Methods: Between January 2011 and December 2012,\nwe retrospectively examined adult patients who met PJI-SIRS criteria. Medical\nhistory search for patientsâ?? anamnesis, surgical times, laboratory-microbiological\nfindings and success rates was performed. Results: Twenty patients\nwere enrolled in this study with a mean age of 71.35 years. Men population\nwas more commonly affected with 55% of the cases. The knee was mainly the\naffected joint with 52%. A severe systemic disease was present in 80% of the\ncases. A sickness sensation and pain were the most common prodromal symptoms\nfound 4.9 days before the admission to the hospital. In 85.7% of the\ncases the etiological agent was identified, with Staphylococcus aureus as the\nmost common. Two-stage surgery treatment was performed with a time interval\nbetween admission and the first operation of 5.45 h. The mean time\nduring the first and second operation was of 23 minutes and 117 minutes respectively.\nA reduction on microbiological positive cultures was found after\nthe first rapid operation (P = 0.0038). Serum CRP levels and fever disappearance\nwere the first parameters which indicated a favorable disease..........................
Background: We aimed to assess the impact of systemic lupus erythematosus (SLE) on the risk of infection after\ntotal hip arthroplasty (THA).\nMethods: We identified patients undergoing primary THA (1996â??2013) in Taiwan National Health Insurance\nResearch Database (NHIRD). Patients were then divided into the SLE and control groups according to the diagnosis\nof SLE. We used 1:1 propensity score to match the control to the SLE group by age, sex, and comorbidities. The\nprimary outcome was infection, including early and late superficial wound infection and periprosthetic joint\ninfection (PJI). The secondary outcome was in-hospital complications.\nResults: We enrolled 325 patients in each group. In the primary outcome, the incidence of early superficial wound\ninfection and PJI was comparable between the SLE and matched-control group. However, the incidence of late\nsuperficial wound infection.........................
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